Ambulatory Pediatrics
Volume 5, Issue 2 , Pages 107-111 , March 2005

Overweight Status of Adolescent Girls With Polycystic Ovary Syndrome: Body Mass Index as Mediator of Quality of Life

  • Maria Trent, MD, MPH

      Affiliations

    • Corresponding Author InformationAddress correspondence to Maria Trent, MD, MPH, Division of General Pediatrics and Adolescent Medicine, Johns Hopkins School of Medicine, 600 North Wolfe St, Park 307, Baltimore, MD 21287
    • ,
  • S. Bryn Austin, ScD

      Affiliations

    • From the Division of General Pediatrics and Adolescent Medicine (Dr Trent), Johns Hopkins School of Medicine, Baltimore, Md; and the Division of Adolescent/Young Adult Medicine (Drs Austin, Rich, and Gordon), Children's Hospital, Harvard Medical School, Boston, Mass
    • ,
  • Michael Rich, MD, MPH

      Affiliations

    • From the Division of General Pediatrics and Adolescent Medicine (Dr Trent), Johns Hopkins School of Medicine, Baltimore, Md; and the Division of Adolescent/Young Adult Medicine (Drs Austin, Rich, and Gordon), Children's Hospital, Harvard Medical School, Boston, Mass
    • ,
  • Catherine M. Gordon, MD, MSc

      Affiliations

    • From the Division of General Pediatrics and Adolescent Medicine (Dr Trent), Johns Hopkins School of Medicine, Baltimore, Md; and the Division of Adolescent/Young Adult Medicine (Drs Austin, Rich, and Gordon), Children's Hospital, Harvard Medical School, Boston, Mass

Received 29 July 2004 ,Accepted 1 November 2004.

REFERENCES 

  1. Trent M , Rich M , Austin SB , Gordon CM . Quality of life in adolescent girls with polycystic ovary syndrome . Arch Pediatr Adolesc Med . 2002;152:556–560
  2. Stein IF , Leventhal ML . Amenorrhea associated with bilateral polycystic ovaries . Am J Obstet Gynecol . 1935;29:181–191
  3. Franks S . Polycystic ovary syndrome . N Engl J Med . 1995;333:853–861
  4. Chang RJ , Nakamura RM , Judd HL , et al.   Insulin resistance in nonobese patients with polycystic ovarian disease . J Clin Endocrinol Metab . 1983;57:356–359
  5. Salehi M , Bravo-Vera R , Sheikh A , et al.   Pathogenesis of polycystic ovary syndrome: What is the role of obesity? . Metabolism . 2004;53:358–376
  6. Dunaif A . Insulin action in the polycystic ovary syndrome . Endocrinol Metab Clinics NA . 1999;28:41–59
  7. Hashimoto DM , Schmid J , Martins FM , et al.   The impact of weight status on subjective symptomatology of the polycystic ovary syndrome: a cross-cultural comparison between Brazilian and Austrian women . Anthropol Anz . 2003;61:297–310
  8. Coffey S , Mason H . The effect of polycystic ovary syndrome on health-related quality of life . Gynecol Endocrinol . 2003;17:379–386
  9. Troiano RP , Flegal KM . Overweight children and adolescents: description, epidemiology, and demographics . Pediatrics . 1998;101:S497–S504
  10. Zawadzki JK , Dunaif A . Diagnostic criteria for polycystic ovary syndrome: towards a rational approach . In: Dunaif A , Givens JR , Haseline F , Mernam GR editor. Polycystic Ovary Syndrome . Boston, Mass: Blackwell Publishers; 1992;p. 377–384
  11. Landraf JM , Abetz L . Functional status and well-being of children representing three cultural groups: initial self-reports using the CHQ-CF87 . Psychol Health . 1997;12:839–854
  12. Landgraf JM , Abetz L , Ware JE . The CHQ User's Manual . 1st ed.. Boston, Mass: The Health Institute, New England Medical Center; 1996;
  13. Waters EB , Salmon LA , Wake M , et al.   The health and well-being of adolescents: a school-based population study of the self-report of the Child Health Questionnaire . J Adolesc Health . 2001;29:140–149
  14. Britto MT , Kotagal UR , Hornug RW , et al.   Impact of recent pulmonary exacerbations on quality of life in patients with cystic fibrosis . Chest . 2002;121:64–72
  15. Wake M , Hesketh K , Cameron F . The Child Health Questionnaire in children with diabetes: cross-sectional survey of parent and adolescent-reported functional health status . Diabet Med . 2000;10:700–707
  16. Ginsberg JP , Cnaan A , Zhao H , et al.   Using health-related quality of life measures to predict cardiac function in survivors exposed to anthracyclines . J Clin Oncol . 2004;22:3149–3155
  17. National Center for Chronic Disease Prevention and Health Promotion. . 1998 Youth Risk Behavior Survey Centers for Disease Control and Prevention . Available at: http://www.cdc.gov/nccdphp Accessed February 15, 2002
  18. Zawadzki JK , Dunaif A . Diagnostic criteria for polycystic ovary syndrome: towards a rational approach . In: Dunaif A , Givens JR , Haseline F , Merriam GR editor. Polycystic Ovary Syndrome . Boston, Mass: Blackwell Publishers; 1992;p. 377–384
  19. National Center for Chronic Disease and Disease Prevention. . Nutrition and Physical Activity Centers for Disease Control and Prevention . Available at: http://www.cdc.gov/nccdphp/dnpa/bmi/bmi-for-age.htm Accessed June 8, 2004
  20. Baron RM , Kenny DA . The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations . J Personality Soc Psychol . 1986;51:1173–1182
  21. Rothman KJ , Greenland S , Rothman S . Modern Epidemiology . Lippincott Williams & Wilkins; 1998;
  22. Friedlander SL , Larkin EK , Rosen CL , et al.   Decreased quality of life associated with obesity in school-aged children . Arch Pediatr Adolesc Med . 2003;157:1206–1211
  23. Schwimmer JB , Burwinkle TM , Varni JW . Health-related quality of life of severely obese children and adolescents . JAMA . 2003;289:1813–1819
  24. Gambineri A , Pelusi C , Vicennati V , et al.   Obesity and the polycystic ovary syndrome . Int J Obesity . 2002;26:883–896
  25. Wright CE , Zborowski JV , Talbott EO , et al.   Dietary intake, physical activity, and obesity in women with polycystic ovary syndrome . Int J Obesity . 2004;28:1026–1032
  26. Knowler WC , Barrett-Connor E , Fowler SE , et al.   Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin . N Engl J Med . 2002;346:393–403
  27. Stamets K , Taylor DS , Kunselman A , et al.   A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome . Fertil Steril . 2004;81:630–637
  28. Pasquali R , Antenucci D , Casimirri F , et al.   Clinical and hormonal characteristics of obese amenorrheic hyperandrogenic women before and after weight loss . J Clin Endocrinol Metab . 1989;68:173–179
  29. Kiddy DS , Hamilton-Fairley D , Bush A , et al.   Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome . Clin Endocrinol . 1992;36:105–111

PII: S1530-1567(05)60179-7

doi: 10.1367/A04-130R.1

Ambulatory Pediatrics
Volume 5, Issue 2 , Pages 107-111 , March 2005

Article Tools